Transplant in times of the beginning of SARS-CoV2 pandemic, experience in reference center public hospital in Mexico
Luis Garcia1,2, Flor Rojas1, Perez Karina1, Diana Fernandez1, Aldo Garcia1, Hector Hinojosa1, Lionel Vargas1.
1Surgery, Hospital General de Mexico Dr. Eduardo Liceaga, Ciudad de Mexico, , Mexico; 2Surgery, Hospital Especialidades CMN SXXI IMSS, Ciudad de Mexico, , Mexico
Introduction: The new coronavirus disease 2019 (COVID-19) had an impact on the health system worldwide after being declared a pandemic, causing the stoppage of solid organ transplants in various countries. In Mexico, once the pandemic was declared, the National Transplant Center for government proclaimed the cessation of activities at the national level, continuing for the following 6 months.
Materials and Methods: Retrospective cohort, included transplant patients at Hospital General de Mexico, from January 2020 to January 2021, with follow-up for a period of 3 months. Descriptive statistics were performed.
Results: 9 patients with deceased donor Kidney Transplant were included, mean age 31.32 ± 7.8 years, 60% male, the main cause of Kidney Disease was undetermined in 77.7%, one of glomerulate basal membrane, and one with nodular diabetic glomerulosclerosis. One patient with preformed DQ7 ADEs, all receive induction with Thymglobulin, and maintenance with triple scheme. During the follow-up there was one hyper acute rejection secondary to non-HLA humoral rejection plus venous thrombosis due to protein S deficiency, a second patient presented an event of acute kidney injury AKIN3, secondary to gastroenteritis due to C. difficile, with complete recovery, the 3rd patient presented Hypovolemic shock, secondary to sub aponeurotic hematoma. 44.4% of patients presented delayed graft function, with stable renal function during follow-up.
Conclusion: During the pandemic, kidney transplantation was safe in our center, compared to keeping patients with replacement therapy with improvement in quality of life and mortality. No cases of receptors with COVID -19 disease was found.
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